Phylactery is when someone's life force is bound to an enchanted object in order to keep themselves indestructible.
- Nimue/The Darkness – Nimue's life force is tethered to the Dark One's Dagger after she becomes the first Dark One.
- Rumplestiltskin – As the Dark One, Rumplestiltskin is currently immortal due to the Darkness inside him being tethered to the Dagger.
- Zelena Mills – Zelena bound her magic and her life force to her pendant, meaning that she is dies, she is respawned from the pendant's magic.
- Glinda – As Glinda has a similar pendant to Zelena's, it can be assumed her life force is also bound to hers.
- In many cultures, anyone who practices phylactery to become immortal is known as a "lich".